Urology · Cancer Screening
PSA – Prostate Specific Antigen
A key blood test for prostate health in men — used to screen for prostate cancer, monitor BPH, and track treatment response.
Prostate Health — What PSA Tells Your Doctor
Prostate Specific Antigen (PSA) is a serine protease enzyme secreted exclusively by prostate gland cells — both normal and cancerous. Its biological role is to liquefy semen after ejaculation. In healthy men, tiny amounts enter the bloodstream; elevated levels suggest the prostate's internal architecture has been disrupted, allowing more PSA to leak — as happens in cancer, inflammation (prostatitis), or benign enlargement (BPH).
While PSA is not a perfect test — it can be elevated without cancer and occasionally normal despite cancer — it remains the best available blood biomarker for early prostate cancer detection. When interpreted alongside PSA velocity (rate of rise), free-to-total PSA ratio, and clinical examination, it is a powerful screening and monitoring tool.
PSA Reference Ranges
| Age | Normal PSA (ng/mL) | Comment |
|---|---|---|
| 40–49 years | < 2.5 ng/mL | Baseline screening age |
| 50–59 years | < 3.5 ng/mL | Annual screening recommended |
| 60–69 years | < 4.5 ng/mL | Higher baseline expected |
| 70+ years | < 6.5 ng/mL | Age-adjusted range |
| Any age > 10 ng/mL | Elevated — high concern | Urgent urology referral |
Who Should Get Tested?
Preparation
No fasting required. Avoid ejaculation for 48 hours before the test — it can temporarily raise PSA. Avoid vigorous cycling or prostate examination for 24–48 hours. Urinary tract infections can also elevate PSA — inform your doctor.
Test Price at Velys Hospital
₹150
Inclusive of collection · Same-day report
Book PSA Test at Velys Hospital
Urology consultation available · Same-day results · NABL-quality lab · Ahmedabad